The Courtyard Clinic

Polynucleotides (Plinest)

Treatment At a Glance


Polynucleotides (Plinest)
Eyes, Face or Body


Face and body : £375 per treatment
Hair : £375 per treatment
Eyes: £400 per treatment

Down Time

1-2 Days



Duration of Results

Face, neck, décolleté and eyes
One session every 14-21 days for 3 to 4 sessions.
Body Phase 1 : every 7-14 days for 4 sessions.
Phase 2: every 21-30 days for a further 4 sessions.
HairPhase 1 : every 7-14 days for 4 sessions.
Phase 2: every 21-30 days for a further 4 sessions. Number of sessions fully required varies for each individual.


Immediate results for the face and body
30-60 days after the second treatment for eyes
Hair : Initial number of treatments required varies on the response to treatment and we will monitor for an adequate response to treatment.
Maintenance for hair:
1 session every 1-2 months.

Plinest and Newest are not fillers or toxins but injectable bio-stimulant gels designed to enhance the skin’s natural regenerative processes. They work by stimulating the production of collagen and promoting the repair of skin tissues, resulting in a noticeable lifting and firming effect.

Perfect for those seeking to restore their skin’s elasticity and achieve a more youthful, contoured appearance, these treatments can be seamlessly integrated into your existing skincare regimen for added benefits. Discover the cutting-edge science of Mastelli at The Courtyard Clinic and experience a new level of skin rejuvenation.


The Benefits

Plinest & Newest
  • Skin Rejuvenation: Utilises highly purified polynucleotides to restore skin health, promoting a more youthful and radiant appearance.

  • Collagen Production: Stimulates fibroblasts to enhance collagen production, improving skin elasticity and firmness.

  • Skin Repair: Aids in the natural repair and regeneration of skin tissues, helping to heal damaged skin.

  • Hydration: Provides deep hydration, improving skin moisture and resilience.

  • Improves Skin Texture: Reduces fine lines, wrinkles, and acne scars, enhancing overall skin texture and tone.

  • Versatile Use: Suitable for various areas including the face, neck, hands, and scalp, addressing multiple skin concerns like aging, pigmentation, and large pores.

Plinest & PlinestOne


For prevention and maintaining younger patients’ skin quality. It helps to remodel areas with a high fibrous content such as acne scars.


For improving periocular skin texture

Plinest Eye is an injectable gel designed for the eye area, improving skin quality by stimulating cell turnover and boosting collagen production. It reduces fine lines, wrinkles, crow’s feet, dark circles, and sagging skin, promoting a fresher, more radiant look.


For trophic action on hair and eyebrows

Plinest Hair is an injectable gel designed to improve scalp and hair quality. It uses polynucleotide technology to stimulate cell turnover, boost collagen production, and enhance elasticity, resulting in healthier hair and scalp. It is effective for treating issues such as hair thinning and hormonal hair loss. The gel promotes fibroblast activity and bio-regeneration, ensuring hydration and improved hair structure from within. Suitable for use on both hair and eyebrows, it provides a comprehensive solution for revitalising hair growth and condition.


Mastelli, in Newest harnesses the power of mannitol to enhance the benefits of linear hyaluronic acid (HA). By incorporating mannitol, Mastelli ensures optimal preservation and stabilisation of HA, resulting in improved longevity and effectiveness.

Used to improve the quality of the skin in more mature patients through:

  • Moisturisation
  • Facilitated Trophism,
  • Improving Turgidity
  • Suppleness.

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